Malware Carb Caps has emerged as a significant threat to end-users, businesses, and governments, resulting in financial losses of billions of dollars.Cybercriminals have found malware to be a lucrative business because of its evolving capabilities and ability to target diverse platforms such as PCs, mobile devices, IoT, and cloud platforms.While pr
Updated knowledge and a proposed nomenclature for nuclear receptors with two DNA binding domains (2DBD-NRs).
Nuclear receptors (NRs) are important transcriptional modulators in metazoans.Typical NRs possess a conserved DNA binding domain (DBD) and a ligand binding domain (LBD).Since we discovered a type of novel NRs each of them has two DBDs and single LBD (2DBD-NRs) more than decade ago, there has been very few studies about 2DBD-NRs.Recently, 2DBD-NRs h
Analysis and Visualization of Coastal Ocean Model Data in the Cloud
The traditional flow of coastal ocean model data is from High-Performance Computing (HPC) centers to the local desktop, or to a file server where just the needed data can be extracted via services such as OPeNDAP.Analysis and visualization are then conducted using local hardware and software.This requires moving large amounts of data across the int
Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam
Nanocrystal is widely applied to improve the dissolution of poorly water-soluble drugs.We aimed to prepare meloxicam (MLX) nanocrystals using the bead mill method, followed by high-pressure homogenization (HPH).Simple drying at room temperature (RD), vacuum-drying (VD), and freeze-drying (FD) using mannitol or trehalose as a cryoprotectant were app